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Artificial uterus


An artificial uterus (or artificial womb) is a theoretical device that would allow for extracorporeal pregnancy or extrauterine fetal incubation (EUFI) by growing an embryo or fetus outside of the body of an organism that would normally internally carry the embryo or fetus to term.

An artificial uterus, as a replacement organ, would have many applications. It could be used to assist male or female couples in the development of a fetus. This can potentially be performed as a switch from a natural uterus to an artificial uterus, thereby moving the threshold of fetal viability to a much earlier stage of pregnancy. In this sense, it can be regarded as a neonatal incubator with very extended functions. Also, it can potentially be used for initiation of fetal development. Furthermore, it could avail for performing, for example, fetal surgery procedures at an early stage instead of having to postpone them until term of pregnancy.

An artificial uterus would have to provide nutrients and oxygen to nurture a fetus, as well as dispose of waste material. The scope of an artificial uterus (or "artificial uterus system" to emphasize a broader scope) may also include the interface serving the function otherwise provided by the placenta, an amniotic tank functioning as the amniotic sac, as well as an umbilical cord.

A woman may still supply nutrients and dispose of waste products if the artificial uterus is connected to her. Also, it may provide immune protection against diseases by passing of IgG antibodies to the embryo or fetus.

Artificial supply and disposal have the potential advantage of allowing the fetus to develop in an environment that is not influenced by the presence of disease, environmental pollutants, alcohol, or drugs which a human may have in the circulatory system. Also, there is no risk of an immune reaction towards the embryo or fetus that could otherwise arise from insufficient gestational immune tolerance. Following are aspects of individual functions of an artificial supplier and disposer:

Theoretically, animal suppliers and disposers may be used, but when involving an animal's uterus the technique may rather be in the scope of interspecific pregnancy.


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