Combination of | |
---|---|
Diclofenac | NSAID |
Misoprostol | Prostaglandin analog |
Clinical data | |
MedlinePlus | a699002 |
Pregnancy category |
|
Routes of administration |
Oral |
ATC code | |
Legal status | |
Legal status |
|
The combination diclofenac/misoprostol (trade name Arthrotec) is a pharmaceutical product that contains:
In the United Kingdom it is available in two strengths. It is marketed by Pharmacia and its indication is for prophylaxis against NSAID-induced gastroduodenal ulceration in patients requiring diclofenac for rheumatoid arthritis or osteoarthritis.
Arthrotec must not be taken during pregnancy, as it may deform or otherwise harm the fetus, or lead to miscarriage. This may be accompanied by potentially dangerous bleeding, possibly requiring surgery and potentially leading to infertility or death. As of 2015 the cost for a typical month of medication in the United States is more than 200 USD.