Apamene
The Syrian tetrapolis consisted of the cities Antioch, Seleucia Pieria, Apamea, and Laodicea in Syria.
The region known as 'Seleucis of Syria' was administered by a Tetrapolis of the four largest cities founded by Seleucus Nicator;
Under the Macedonian kings, Upper Syria (Syria Superior) was divided into four parts (tetrarchies) which were named after their capitals;
Under the Romans, the province was divided into nine districts :
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