The Italian parliamentary Antimafia Commission (Italian: Commissione parlamentare antimafia) is a bicameral commission of the Italian Parliament, composed of members from the Chamber of Deputies and the Senate. The first commission, formed in 1963, was established as a body of inquiry tasked with investigating the "phenomenon of the [Sicilian] Mafia". Subsequent commissions expanded their scope to investigate all "organized crime of the Mafia type", which included other major criminal organizations in Italy such as the Camorra, the 'Ndrangheta and the Sacra Corona Unita.
The Commission's goal is to study the phenomenon of organized crime in all its forms and to measure the adequacy of existing anti-crime measures, legislative and administrative, according to their results. The Commission also has judicial powers in that it may instruct the judicial police to carry out investigations, it can ask for copies of court proceedings, and is entitled to request any form of collaboration that it deems necessary. Those who provide testimony to the Commission are obliged by law to tell the truth. The Commission can also submit reports to the Parliament as often as desired, but does so at least on an annual basis.
The first proposal to constitute a commission of inquiry into the Mafia was the result of post-war struggles for land reform and the violent reaction against peasant organizations and its leaders, culminating in the killing of 11 people and the wounding of over thirty at a May 1 labour day parade in Portella della Ginestra. The attack was attributed to the bandit and separatist leader Salvatore Giuliano. Nevertheless, the Mafia was suspected of involvement in the Portella della Ginestra massacre and many other previous and subsequent attacks.