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Andrej Sali

Andrej Šali
Andrej Sali.jpg
Andrej Šali speaking at ISMB 2012.
Born 1963 (age 53–54)
Institutions University of California, San Francisco
Harvard University
Rockefeller University
Birkbeck College, University of London
University of Ljubljana
Alma mater Birkbeck College, University of London
Thesis Modelling three-dimensional structure of a protein from its amino acid sequence (1991)
Doctoral advisor Tom Blundell
Notable students Ilya Vakser
Roberto Sanchez
Andras Fiser
Bino John
Maya Topf
Francisco Melo
M.S. Madhusudhan
Frank Alber
Rachel Karchin
David Barkan
Website
www.salilab.org

Andrej Šali (born 1963, Kranj, Slovenia) is a computational structural biologist. Since 2003, he has been Professor in the Department of Bioengineering and Therapeutic Sciences at University of California, San Francisco. He also serves as an editor of the journal Structure.

Šali received his Bachelor of Science degree in Chemistry from University of Ljubljana, 1987; his Ph.D. in Molecular Biophysics from Birkbeck College,University of London, 1991 (working with Tom Blundell); and did postdoctoral work at Harvard University (working with Martin Karplus).

Sali joined the faculty of the Rockefeller University in 1995, following his postdoctoral research at Harvard University. He is using computation grounded in the laws of physics and evolution to study the structure and function of proteins. For example, he developed comparative protein structure modeling by satisfaction of spatial restraints, implemented in program MODELLER and integrative structure determination of macromolecular assemblies, implemented in program IMP.

Sali contributes to structural biology by developing and applying computational methods for structural modeling and analysis of proteins. The two most often used programs developed by his research group include MODELLER for comparative protein structure modeling and IMP for integrative structure determination.


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