Andrej Šali | |
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Andrej Šali speaking at ISMB 2012.
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Born | 1963 (age 53–54) |
Institutions |
University of California, San Francisco Harvard University Rockefeller University Birkbeck College, University of London University of Ljubljana |
Alma mater | Birkbeck College, University of London |
Thesis | Modelling three-dimensional structure of a protein from its amino acid sequence (1991) |
Doctoral advisor | Tom Blundell |
Notable students | Ilya Vakser Roberto Sanchez Andras Fiser Bino John Maya Topf Francisco Melo M.S. Madhusudhan Frank Alber Rachel Karchin David Barkan |
Website www |
Andrej Šali (born 1963, Kranj, Slovenia) is a computational structural biologist. Since 2003, he has been Professor in the Department of Bioengineering and Therapeutic Sciences at University of California, San Francisco. He also serves as an editor of the journal Structure.
Šali received his Bachelor of Science degree in Chemistry from University of Ljubljana, 1987; his Ph.D. in Molecular Biophysics from Birkbeck College,University of London, 1991 (working with Tom Blundell); and did postdoctoral work at Harvard University (working with Martin Karplus).
Sali joined the faculty of the Rockefeller University in 1995, following his postdoctoral research at Harvard University. He is using computation grounded in the laws of physics and evolution to study the structure and function of proteins. For example, he developed comparative protein structure modeling by satisfaction of spatial restraints, implemented in program MODELLER and integrative structure determination of macromolecular assemblies, implemented in program IMP.
Sali contributes to structural biology by developing and applying computational methods for structural modeling and analysis of proteins. The two most often used programs developed by his research group include MODELLER for comparative protein structure modeling and IMP for integrative structure determination.