Andrés Pacheco (1550–1626) was a Spanish churchman and theologian.
Andrés Pacheco was born in La Puebla de Montalbán on April 5, 1550. His father was Alonso Pacheco y Téllez-Girón, Lord of La Puebla de Montalbánm, who was a Knight of the Order of Santiago and commander of Medina de las Torres. His mother was Juana de Cárdenas, daughter of Alonso de Cárdenas, Conde of Puebla del Maestre.
He studied grammar, dialectic, philosophy, and theology at the University of Alcalá, graduating with a doctorate in theology. Philip II of Spain named Pacheco tutor of his nephew Albert VII, Archduke of Austria, who later became a cardinal and Governor of the Habsburg Netherlands. Pacheco later became Abbot of San Vicente de la Sierra (connected to the Cathedral of Toledo) and of then of the Cathedral of Alcalá de Henares (1584–87).
On December 2, 1587, the cathedral chapter of the Segovia Cathedral elected Pacheco bishop of Segovia; during his time as bishop of Segovia, he held a diocesan synod. He was translated on August 13, 1601, becoming Bishop of Cuenca.