And I Feel Fine... The Best of the I.R.S. Years 1982–1987 is a compilation album by R.E.M. that features songs from the band's years at I.R.S. Records. All tracks have been remastered, and the set was released 12 September 2006. A companion DVD, called When the Light Is Mine, was released the same day.

And I Feel Fine is available in three versions: a standard one-disc version with 21 fan-favorite tracks spanning the Chronic Town EP from 1982 to Document from 1987 including every song released as a single on I.R.S. except for "Wendell Gee" and "Superman;", a second edition that adds a bonus disc including rarities, the "Superman" single, unreleased songs, and alternate mixes, and a third edition, which combines the two disc version with the When the Light Is Mine DVD.

Two songs, "Bad Day" and "All the Right Friends," appear in outtake versions here, as opposed to final versions on the 2003 Warner Bros. R.E.M. compilation In Time: The Best of R.E.M. 1988–2003. The songs "Theme from Two Steps Onward" and "Mystery to Me" were previously unreleased in any form and, like the version of "Bad Day," were Lifes Rich Pageant outtakes. The band had originally intended to include "Theme from Two Steps Onward" as an exclusive track on Eponymous but had lost the tape. Demo versions of all four songs recorded during the Lifes Rich Pageant sessions were later released on the 25th Anniversary Edition of that album.

And I Feel Fine... The Best of the I.R.S. Years 1982–1987 reached #70 in the UK Albums Chart. In the U.S., each version charted separately, with the two-disc version reaching a higher peak than the single-disc version.

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