Anastase Stolojan (August 6, 1836–July 25, 1901) was a Wallachian-born Romanian politician.
Born in Craiova, he descended from a family of small-scale boyars that came from Stolojani village in Gorj County. His father State was a vistier (treasurer). He attended school in his native city before continuing his education in France. In 1863, he graduated from the law faculty of the University of Paris, in the process earning a doctorate. Stolojan entered the magistracy at Craiova in 1865, becoming a prosecutor for the Dolj County tribunal and the appeals court. In 1868, he served as mayor of Craiova. Politically liberal and a close associate of C. A. Rosetti, he was first elected to the Assembly of Deputies in 1869, with support from both liberals and their opposition. He was a supporter of the 1870 Republic of Ploiești conspiracy, and letters with compromising instructions from Rosetti were found in his possession.
Stolojan was a signatory of the National Liberal Party's initial program in 1875. In April 1877, he and Alexandru Candiano-Popescu drafted a resolution calling for the government to launch the Romanian War of Independence. He served in several Liberal cabinets. Under Ion C. Brătianu, he was Justice Minister from July 1879 to July 1880, and was interim Interior Minister for four days in July 1880. Then, from February 1885 to October 1886, he was Minister of Agriculture, Domains, Industry and Commerce. Under Dimitrie A. Sturdza, he was Interior Minister from February to November 1896 and again held the Agriculture portfolio from March 1897 to January 1899.