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Amount of substance


Amount of substance is a standards-defined quantity that measures the size of an ensemble of elementary entities, such as atoms, molecules, electrons, and other particles. It is sometimes referred to as chemical amount. The International System of Units (SI) defines the amount of substance to be proportional to the number of elementary entities present. The SI unit for amount of substance is the mole. It has the unit symbol mol. The proportionality constant is the inverse of the Avogadro constant.

The mole is defined as the amount of substance that contains an equal number of elementary entities as there are atoms in 12g of the isotope carbon-12. This number is called Avogadro's number and has the value 6.022140857(74)×1023. It is the numerical value of the Avogadro constant which has the unit 1/mol, and relates the molar mass of an amount of substance to its mass. Therefore, the amount of substance of a sample is calculated as the sample mass divided by the molar mass of the substance.

Amount of substance appears in thermodynamic relations such as the ideal gas law, and in stoichiometric relations between reacting molecules as in the law of multiple proportions.

Another unit of amount of substance in use in chemical engineering in the United States is the pound-mole, having the symbol lb-mol. One pound-mole is 453.59237 mol.


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