Amino esters

Amino esters are a class of local anesthetics.

Structurally, local anesthetics consist of three molecular components:

The chemical linkage between the lipophilic part and the intermediate chain can be of the amide-type or the ester-type, and is the general basis for the current classification of local anesthetics.

Amino esters, in reference to anesthetic agents, are rapidly metabolized in the plasma by butyrlcholinesterase to para-aminobenzoic acid derivatives, then excreted in the urine. This suggests their very short half lives. Allergy is more likely to occur with ester-type agents, as opposed to amide-type.

Amino ester-type include:

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