Sir Amyas Bampfylde (alias "Amias Bampfield" etc.) (1560 – 9 February 1626) of Poltimore and North Molton in Devon, England, was Member of Parliament for Devon in 1597.
Bampfylde was the son of Richard Bampfield (1526–1594), of Poltimore and Bampfylde House in Exeter, Devon, Sheriff of Devon in 1576, (whose monument survives in Poltimore Church) by his wife Elizabeth Sydenham (died 1599), daughter of Sir John Sydenham of Brympton d'Evercy, Somerset.
He matriculated at Exeter College, Oxford on 3 December 1575, aged 15. He studied law at the Middle Temple in 1576. He succeeded to the manor of Poltimore on the death of his father in 1594. He was J.P. for Devon from 1596. In 1597, he was elected Member of Parliament for Devon. He was knighted at Windsor on 9 July 1603. He was Sheriff of Devon from 1603 to 1604. In 1616 he was Deputy Lieutenant.
In 1576 Bampfylde married Elizabeth Clifton, a daughter of Sir John Clifton (died 1593) of Barrington Court, Somerset, by his wife Anne Stanley, daughter of Thomas Stanley, 2nd Baron Monteagle (1507–1560). Sir John Clifton's father was a London merchant, Sir William Clifton (died 1564), who had purchased the manor of Barrington from Henry Grey, 1st Duke of Suffolk. Elizabeth Clifton's brother was Gervase Clifton, 1st Baron Clifton (c. 1570 – 1618). Her portrait circa 1640, in the style of Anthony van Dyck, survives in the collection of Antony House, Cornwall and her stone-sculpted effigy sits in mourning next to the recumbent one of her husband in North Molton Church, on which monument are depicted the arms of Bampfylde impaling Clifton: Argent semée of cinquefoils pierced gules, a lion rampant of the last. By his wife he had six sons and four daughters as follows: