The American Physiological Society (APS) was founded in 1887 with 28 members. Of them, 21 were graduates of medical schools, but only 12 had studied in institutions that had a professor of physiology. Today, the APS has 10,500 members, most of whom hold doctoral degrees in medicine, physiology or other health professions. APS's mission then, as now, is to support research, education, and circulation of information in the physiological sciences.
The American Physiological Society was founded at a time when very few physiological laboratories existed in America and there were few investigators. The newly established society was one of the earliest national disciplinary societies in the sciences, the first society in the biomedical sciences, and likely the first to require its members to publish original research. The stated object of the Society was to promote the advancement of physiology and to facilitate discourse among American physiologists. Even in 1887 there was a conscious effort to ensure representation of all areas within physiology, encompassing topics as diverse as neurology, psychology, ophthalmology, pathology and therapeutics, as well as plant physiology and animal biology. Today there are a variety of membership categories for those at all interest levels and ages.
Since it was founded in 1887, the APS has had 86 presidents lead the organization, beginning with founder Henry Bowditch and continuing through its current president, Kim E. Barrett. The APS is governed by an elected Council consisting of the President, the President-Elect, the immediate Past President, and nine Councillors. Management of the affairs of the Society is the responsibility of a full-time Executive Director, appointed by and responsible to the Council. The Society maintains a staff and offices on the campus of the Federation of American Societies for Experimental Biology (FASEB) in Bethesda, Maryland. The Society conducts its operations based on a Constitution and Bylaws, as given in the Society's Operational Guide. As a nonprofit scientific organization, the Society holds tax-exempt status. The organization is managed by Executive Director Martin Frank, PhD., a physiologist by training.