The Alkali Lake Indian Band, also known as the Esketemc First Nation, is a First Nations government of the Secwepemc (Shuswap) people, located at Alkali Lake in the Cariboo region of the Central Interior of the Canadian province of British Columbia. It was created when the government of the then-Colony of British Columbia established an Indian Reserve system in the 1860s. It is one of three Secwepemc bands that is not a member of either the Shuswap Nation Tribal Council or the Northern Shuswap Tribal Council.
In the Shuswap language, the people of Alkali Lake are the Esketemc ("people of Esket").
Indian Reserves under the administration of the Esketemc First Nation are: