Native Americans in the United States have historically had extreme difficulty with the use of alcohol. Problems continue among contemporary Native Americans; 12% of the deaths among Native Americans and Alaska Natives are alcohol-related. Use of alcohol varies by age, gender and tribe with women, and older women in particular, being least likely to be regular drinkers. Native Americans, particularly women, are more likely to abstain entirely from alcohol than the general US population. Frequency of use among Native Americans is generally less than the general population, but the quantity consumed when it is consumed is generally greater.
A survey of death certificates over a four-year period showed that deaths among Native Americans due to alcohol are about four times as common as in the general US population and are often due to traffic collisions and liver disease with homicide, suicide, and falls also contributing. Deaths due to alcohol among Native Americans are more common in men and among Northern Plains Indians. Alaska Natives showed the least incidence of death. Alcohol abuse by Native Americans has been shown to be associated with development of disease, including sprains and muscle strains, hearing and vision problems, kidney and bladder problems, head injuries, pneumonia, tuberculosis, dental problems, liver problems, and pancreatitis. In some tribes, the rate of fetal alcohol spectrum disorder is as high as 1.5 to 2.5 per 1000 live births, more than seven times the national average, while among Alaska natives, the rate of fetal alcohol spectrum disorder is 5.6 per 1000 live births.
Native American youth are far more likely to experiment with alcohol than other youth with 80% alcohol use reported. Low self-esteem is thought to be one cause. Active efforts are underway to build self-esteem among youth and to combat alcoholism among Native Americans.