In Greek mythology, Alcmaeon (Greek: Ἀλκμαίων), was the son of Amphiaraus and Eriphyle. As one of the Epigoni, he was a leader of the Argives who attacked Thebes, taking the city in retaliation for the deaths of their fathers, the Seven Against Thebes, who died while attempting the same thing.
Pindar's eighth Pythian ode relates a prophecy by Amphiaraus that the Epigoni will conquer Thebes, and that Alcmaeon will be the first through the gates. The Bibliotheca also states that the other Epigoni received an oracle instructing them to make Alcmaeon their leader, and therefore convinced him to go with them, although he was unwilling. In Diodorus, Eriphyle persuades her son to join the attackers because she is bribed by Thersander to do so in exchange for the robe of Harmonia, just as she was bribed by Polynices with the necklace of Harmonia to send her husband into battle. However, according to Asclepiades of Tragilus, Amphiaraus orders Alcmaeon to avenge him on Eriphyle as soon as he is old enough, making it clear that at least two traditions are present. In most versions, he kills Laodamas, the son of Eteocles, in the battle.
Although sources differ concerning whether Alcmaeon knew about his mother's treachery before he attacked Thebes, all agree that once he returned he killed his mother, possibly with the help of his younger brother Amphhilochus. For committing matricide, he was pursued by the Erinyes and driven mad, fleeing first to Arcadia, where his grandfather Oicles ruled, and then to King Phegeus in Psophis, who purified him and gave him his daughter, Arsinoe (named Alphesiboea in some versions) in Pseudo-Apollodorus and Alphesiboea in Pausanias, in marriage. Alcmaeon gave her the necklace and robe of Harmonia. According to Pseudo-Apollodorus, Alcmaeon's presence caused the land to be infertile, so he went to Delphi for assistance. In Pausanias, it is his own madness which drove him to do so.