"Again" is a song by Alice in Chains, released on their album Alice in Chains (1995). The song was included on the compilation albums Nothing Safe: Best of the Box (1999), Greatest Hits (2001), and The Essential Alice in Chains (2006). A remixed version of the song was included on the box set Music Bank (1999).

"Again" was released as a single in 1996. "Again" peaked at number eight on the Billboard Mainstream Rock Tracks chart and at number 36 on the Billboard Modern Rock Tracks chart. The song was nominated for the Grammy Award for Best Hard Rock Performance in 1997.

In the liner notes of 1999's Music Bank box set collection, guitarist Jerry Cantrell said of the song:

This guy, Praga Kahn, did three different mixes. One I didn't like, the second one (Trip hop Mix) had horns and strings without too many guitars or drums, which I kinda liked. Then there was [the "Tattoo of Pain Mix"], which was cool too. We put a couple out as "B" sides in Europe. Personally, I never got used to the idea that you had to give some places extra songs and not others, it should be the same for everybody as far as I'm concerned.

The music video for "Again" was released in 1996 and was co-directed by George Vale and vocalist Layne Staley. The music video was nominated for Best Hard Rock Video at the 1996 MTV Video Music Awards. The video is available on the home video release Music Bank: The Videos and is the final Alice in Chains music video that Layne Staley filmed with the band (future videos featured only archived footage of the singer).

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