The 42nd Vanier Cup was played on November 25, 2006, at Griffiths Stadium in Saskatoon, Saskatchewan, and decided the CIS Football champion for the 2006 season. The hometown Saskatchewan Huskies lost their CIS record third straight Vanier Cup to the Laval Rouge et Or by a score of 13-8. Laval became the second team in CIS history to win three championships over a four-year period after the Western Ontario Mustangs won in 1974, 1976, and 1977.

Laval Rouge et Or (13) - TDs, Guillaume Allard-Caméus; FGs, Cameron Takacs (2); cons., Cameron Takacs (1).

Saskatchewan Huskies (8) - TDs, Tyler O’Gorman; safety touch (1).