2016 Hall of Fame Tennis Championships – Singles
| Singles | |
|---|---|
| 2016 Hall of Fame Tennis Championships | |
| Champion |
 Ivo Karlović
|
| Runner-up |
 Gilles Müller
|
| Final score | 6–7(2–7), 7–6(7–5), 7–6(14–12) |
Rajeev Ram was the defending champion, but lost in the second round to Dudi Sela.
Ivo Karlović won the title, defeating Gilles Müller in the final, 6–7(2–7), 7–6(7–5), 7–6(14–12).
The top four seeds receive a bye into the second round.
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