2016 Columbus Challenger 2 – Singles
| Singles | |
|---|---|
| 2016 Columbus Challenger 2 | |
| Champion |
 Stefan Kozlov
|
| Runner-up |
Tennys Sandgren
|
| Final score | 6–1, 2–6, 6–2 |
Mikael Torpegaard was the defending champion but lost in the first round to Taylor Fritz.
Stefan Kozlov won the title after defeating Tennys Sandgren 6–1, 2–6, 6–2 in the final.
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