The 2016–17 San Antonio Spurs season is the 50th season of the franchise, 41st in the National Basketball Association (NBA) and 44th in the San Antonio area. It will be the first season since the 1996–97 season without Tim Duncan, who retired on July 11, 2016. With the elimination of the Detroit Red Wings from the 2017 Stanley Cup playoffs on March 28, 2017, the San Antonio Spurs now hold the longest active playoff streak in any of the major North American professional sports leagues with 20 consecutive NBA Playoffs appearances.

The 2016 NBA draft was held on June 23, 2016, at the Barclays Center in Brooklyn. Spurs chose guard Dejounte Murray with the 29th pick of the first round.

On July 11, Tim Duncan announces retirement.

On July 19, it was confirmed that the Spurs would play a game at the Mexico City Arena in Mexico City, Mexico on January 14, 2017 against the Phoenix Suns.

On March 08, with a 114-104 win over the Sacramento Kings the Spurs extended their league record for consecutive 50+ win seasons to 18 straight.

On April 04, with a 95–89(OT) win over the Memphis Grizzlies the Spurs secured their first back to back 60+ win seasons in team history.