2015 Knoxville Challenger – Singles
| Singles | |
|---|---|
| 2015 Knoxville Challenger | |
| Champion |
 Daniel Evans
|
| Runner-up |
 Frances Tiafoe
|
| Final score | 5–7, 6–1, 6–3 |
Adrian Mannarino was the defending champion, but chose not to compete this year.
Daniel Evans won the title , defeating Frances Tiafoe in the final 5–7, 6–1, 6–3 .
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