The 2012 Gildan New Mexico Bowl was a post-season American college football bowl game that was held on December 15, 2012, at University Stadium on the campus of the University of New Mexico in Albuquerque, New Mexico in the United States. The seventh edition of the New Mexico Bowl began at 11:00 a.m. MST and aired on ESPN. It featured the Nevada Wolf Pack, who represented the Mountain West Conference in their first year as a member, against the Arizona Wildcats, who represented the Pac-12 Conference. The Wolf Pack accepted their invitation with a 7–4 record in their first eleven games of the season, while the Wildcats accepted their invitation after finishing the regular season at 7–5. The bowl was the first of 35 played in the 2012–13 bowl game season.

Coming into the game, both teams had sound offenses and were led by their respective running backs, sophomore Ka'Deem Carey for Arizona and senior Stefphon Jefferson for Nevada, who ranked number one and number two respectively in total rushing yards during the regular season. Arizona and Nevada ranked third and fourth respectively in total offense. Both teams' defenses were ranked towards the bottom of college football. Consequently, the game was widely expected to be high-scoring.

Arizona won the game 49–48 after scoring two touchdowns in the final two minutes to come back for the victory. As expected, the game was dominated by offense; Arizona and Nevada combined for 1234 total yards and 70 first downs. Despite losing the game, Nevada possessed the ball nearly twice as long and gained twice as many rushing yards as Arizona. Arizona quarterback Matt Scott was named the game's offensive most valuable player (MVP), and teammate Marquis Flowers, a linebacker, was named the game's defensive MVP.

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