2012 Knoxville Challenger – Singles
| Singles | |
|---|---|
| 2012 Knoxville Challenger | |
| Champion |
 Michael Russell
|
| Runner-up |
Bobby Reynolds
|
| Final score | 6–3, 6–2 |
Jesse Levine was the defending champion but was defeated in the First Round by Tennys Sandgren.
Michael Russell won the final 6–3, 6–2 against Bobby Reynolds.
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