The 2012 CFL season was the 59th season of modern Canadian professional football. Officially, it was the 55th season for the Canadian Football League. The pre-season began on June 13, 2012 and the regular season started on June 29, 2012.Rogers Centre in Toronto hosted the 100th Grey Cup on November 25, with the hometown Toronto Argonauts defeating the Calgary Stampeders 35-22.

According to the new collective bargaining agreement, the 2012 salary cap will be set at $4,350,000. As per the agreement, the cap is fixed and will not vary with league revenue performance. The minimum team salary will be set at $4,000,000 with individual minimum salaries set at $44,000.

The 2012 season schedule was released on February 18, 2012, with the regular season opening on June 29 at Ivor Wynne Stadium in Hamilton, Ontario. This marked the first time Hamilton has opened the year since 2009. Additionally, the league returned to division match-ups in the final week of the regular season, which was also last seen in 2009. Following an interruption in the Labour Day Classic in 2011 between the Toronto Argonauts and Hamilton Tiger-Cats, the two teams resumed their historic series in 2012. There were 15 double headers this year, with four on Fridays, eight on Saturdays, one on Sundays, and two (the traditional Labour Day and Thanksgiving contests) on Mondays.

The BC Lions opened their regular season schedule at the newly refurbished BC Place Stadium and spent their first full season there after splitting time between that stadium and Empire Field in 2011. The Winnipeg Blue Bombers spent the first four weeks of the regular season on the road as their home opener at the brand new Investors Group Field was to take place in week 5; however, construction delays pushed back the opening of the new stadium to 2013, forcing the Blue Bombers to continue playing at Canad Inns Stadium during the season. The Tiger-Cats played—and won—their final regular season home game at Ivor Wynne Stadium on October 27 as the stadium will be demolished following the 2012 season. Unlike the previous two seasons, there was no game played in Moncton, New Brunswick as part of the Touchdown Atlantic promotion, due to the league wanting to focus on plans for the 100th Grey Cup festival.

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