The 2012–13 season was Oud-Heverlee Leuven's 11th competitive season in professional football. It was their second season in the Belgian Pro League. A promising start by OH Leuven and a 5-match winning streak in October resulted in a third place after 13 matchdays, but thereafter the team dropped in the standings to finally end 10th. In the playoffs, OH Leuven won their group but then lost the playoff final to Gent. In the Belgian Cup, OHL immediately lost their first match just like the previous season, this time going out to Oostende.

On April 27, a first transfer for the new season is announced, as Belgian defender Kenny Thompson signs for OHL, coming from Lierse and two weeks later on May 14, OHL also signs Christopher Verbist from Standard Liège. Verbist played an impressive 2011-12 season in the Belgian Second Division, as he was on loan to Second Division champions Charleroi from Standard Liège.

On May 25, there is a lot of transfer activity at OHL, as two players leave and one is signed. Both Wingback Lionel Gendarme and central defender Pieter Nys decide to sign with a second division team. Gendarme moves to Oostende, while Nys moves to Dutch side Sparta. Meanwhile, on the same day, OHL confirms the signature of Günther Vanaudenaerde from recently relegated Westerlo. Due to injury, Vanaudenaerde missed most of the previous season.

Being founded in 2002, Oud-Heverlee Leuven celebrates its tenth anniversary. During the festivities, results of the "merit" award are presented. Through a web poll, the OHL fans chose François Sterchele as the player having the most merit during the ten inaugural years. Sterchele played for OHL during the 2004-05 season, in which OHL successfully promoted to the Belgian Second Division, with Sterchele the club top scorer, including eight goals during the promotion playoffs. Other players completing the top 5 were (in order): Bjorn Ruytinx, Jordan Remacle, Joeri Vastmans and Hans Goethuys.

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