The 2011-12 FC Shakhtar Donetsk season saw the club complete a domestic double, winning their seventh Ukrainian Premier League and eight Ukrainian Cup whilst losing the Ukrainian Super Cup to FC Dynamo Kyiv. Shakhtar also competed in the UEFA Champions League, where they finished fourth in their group, and were eliminated from the competition.

Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

In: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Out: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

In: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.

Out: Note: Flags indicate national team as defined under FIFA eligibility rules. Players may hold more than one non-FIFA nationality.