The women's 100 metres at the 2010 World Junior Championships in Athletics was held at the Moncton 2010 Stadium on 20 & 21 July.
Prior to the competition, the existing world junior and championship records were as follows.
No new records were established during the competition.
21 July
Wind: -0.7 m/s
21 July
Wind: +1.7 m/s
Wind: +1.6 m/s
Wind: +1.2 m/s
20 July
Wind: +0.3 m/s
Wind: +0.2 m/s
Wind: +0.2 m/s
Wind: +0.1 m/s
Wind: 0.0 m/s
Wind: +0.3 m/s
According to an unofficial count, 41 athletes from 34 countries participated in the event.