2010 Big 12 football standings
	Conf				Overall
Team		W		L		W		L
Northern Division
#20 Nebraska xy		6	–	2		10	–	4
#18 Missouri x		6	–	2		10	–	3
Kansas State		3	–	5		7	–	6
Iowa State		3	–	5		5	–	7
Colorado		2	–	6		5	–	7
Kansas		1	–	7		3	–	9
Southern Division
#6 Oklahoma xy$		6	–	2		12	–	2
#13 Oklahoma State x		6	–	2		11	–	2
#19 Texas A&M x		6	–	2		9	–	4
Baylor		4	–	4		7	–	6
Texas Tech		3	–	5		8	–	5
Texas		2	–	6		5	–	7
Championship: Oklahoma 23, Nebraska 20
$ – BCS representative as conference champion x – Division champion/co-champions y – Championship game participant Rankings from AP Poll

The 2010 Texas Longhorns football team (variously "Texas", "UT", the "Longhorns", or the "'Horns") represented the University of Texas at Austin in the 2010 NCAA Division I FBS football season. The team was coached by Mack Brown, who has a contract lasting through the 2016 season. The Longhorns played their home games in Darrell K Royal–Texas Memorial Stadium and are members of the south division of the Big 12 Conference. Texas finished the season 5–7, 2–6 in Big 12 play. It was the Longhorns' first losing season since 1997.

The Rice Owls and Texas met in 2010 for the 92nd time. Texas held a 69–21–1 lead in the series, which began in 1914. For the Longhorns this series ranks fourth in number of games played, behind Texas A&M, Oklahoma, and Baylor. The two schools were once conference foes in the Southwest Conference and have maintained a rivalry despite the fact that Texas enjoys a sizable lead in the series. President John F. Kennedy alluded to the lopsidedness of the rivalry in his 1962 speech on America's space program: "But why, some say, the moon? ... And they may well ask why climb the highest mountain. Why, 35 years ago, fly the Atlantic? Why does Rice play Texas? ... We choose to go to the moon ... and do the other things, not because they are easy, but because they are hard." In addition to continuing a traditional rivalry, playing Rice in a home and away series allows for Texas to play games in Houston, Texas, an important recruiting base for UT, which has a significant Texas Exes alumni population. During the game, the Owls took an early lead with a field goal in the first quarter. Rice had also forced a turnover on downs. By the end of the first quarter, Rice was in the lead at 3–0. However, in the second quarter, Texas scored 3 touchdowns and 1 field goal. 2 of those touchdowns were rushes from Tre' Newton and the other was from a fumble return. By halftime, Texas was in the lead 24–10. In the second half, both Texas and Rice had calmed down, scoring 10 and 7 points, respectively. The final score would be 34–17, with Texas having the upper hand in total yardage. The game was played at Reliant Stadium.

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