The 2010 FedEx Orange Bowl game featured the Georgia Tech Yellow Jackets and the Iowa Hawkeyes on Tuesday, January 5, 2010, at Land Shark Stadium in Miami Gardens, Florida. Iowa won the game 24–14, securing the Hawkeyes' first major bowl win since the 1959 Rose Bowl.

Georgia Tech was selected to participate in the Orange Bowl after an 11–2 season that culminated in a 39–34 victory in the 2009 ACC Championship Game. Iowa was selected as the other half of the matchup after a 10–2 season that ended with a 12–0 win against Minnesota. In the weeks between the teams' selection and the playing of the game, media attention focused on Georgia Tech's proficient offense and Iowa's highly rated defense.

The game was part of the 2009–2010 Bowl Championship Series (BCS) of the 2009 NCAA Division I FBS football season and the last game of the season for both teams. It was the coldest Orange Bowl in Miami's history with a kick-off temperature of 49 degrees.

The game was televised in the United States on FOX, and marked the end of the broadcast agreement between the BCS and FOX, as ESPN took over all BCS broadcast rights in 2011. This was Iowa's second Orange Bowl appearance (first appearance in 2003 Orange Bowl), and Georgia Tech's sixth appearance, but first since 1967. It was the first time that the two teams had played against each other.

On July 14, 2011, the NCAA vacated Georgia Tech's appearance in the bowl game as a consequence for violations committed by the football program.

The Orange Bowl is one of five Bowl Championship Series (BCS) bowl games that have been played at the conclusion of every college football season since 2006. As defined by contract, the bowl matches the champion of the Atlantic Coast Conference (ACC) against an at-large pick chosen by a special committee. On December 5, 2009, the Georgia Tech Yellow Jackets defeated the Clemson Tigers in the 2009 ACC Championship Game, thus winning an automatic bid to the 2010 Orange Bowl Game.

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