This page provides the summaries of the CAF second round matches for the 2010 FIFA World Cup qualification and the 2010 Africa Cup of Nations. The 48 qualifiers (45 direct entrants plus 3 winners of the first round) were split into 12 groups of four in the draw held in Durban, South Africa on 25 November 2007. Teams in each group played a home-and-away round-robin in 2008, with the 12 groups winners and 8 best runners-up advancing to the third round. As not all groups were of equal size after the exclusion of Ethiopia and the withdrawal of Eritrea, when ranking the runners-up, their results against their group's 4th placed team would not be counted.
One team from each of the following pots was drawn into each group.
Cameroon
Nigeria
Ivory Coast
Morocco
Ghana
Tunisia
Egypt
Guinea
Senegal
Mali
Angola
Togo