The 2010–11 season was Associazione Calcio Milan's 77th season in Serie A, and their 28th consecutive season in the top flight of Italian football. It was the first season under new head coach Massimiliano Allegri, who replaced Leonardo, and with new shirt sponsors Fly Emirates, after four seasons with Bwin.

Milan secured its 18th Serie A title – their first since 2003–04 – with a goalless draw away against Roma on 7 May. The club also competed in the Champions League, being knocked out by Tottenham Hotspur in the round of 16, and they took part in the Coppa Italia as well, reaching the semi-finals, where they were eliminated by Palermo.

For the second-straight year, Milan opened their pre-season by taking on Varese in an away game, on 25 July. Unlike the previous year, however, they suffered a 2–0 defeat, with first-half goals from Daniele Buzzegoli and Marco Cellini.

As part of the Emirates Cup, Milan then played two friendlies against Arsenal and Lyon at the Emirates Stadium, London, on 31 July and 1 August respectively. Both games finished 1–1. Alexandre Pato headed an equalizer late in the second half against Arsenal, after the English club had gone ahead through Marouane Chamakh. Meanwhile, Marco Borriello opened the scoring against Lyon before Jimmy Briand tied the game with 12 minutes to play. The tournament was eventually won by Arsenal.

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