The 2007–08 Liga Vitalis season started on 18 August 2007. The fixtures (or schedule of games to be played) were announced on 12 July 2007.
Fátima and Freamunde were promoted to the Liga Vitalis.
The season is scheduled to end on 11 May 2008.
The first goalscorer of the season was Tatu, who scored a 4th-minute goal for Desportivo das Aves against Olhanense in, one of the four games, the kick-off that ended 1-2 for Olhanense.
The first red card of the season was given to Desportivo das Aves' Sérgio Nunes in the same game.