2006 Pacific Life Open – Men's Singles
| Men's Singles | |
|---|---|
| 2006 Pacific Life Open | |
| Champion |
 Roger Federer
|
| Runner-up |
 James Blake
|
| Final score | 7–5, 6–3, 6–0 |
The 2006 Pacific Life Open – Men's Singles was the main event of the 2006 Pacific Life Open men's tennis tournament played in Indian Wells, USA from March 6 through March 19, 2006.
First-seeded Roger Federer of Switzerland was the two-time defending champion, and won again, defeating James Blake in the final 7–5, 6–3, 6–0.
All seeds receive a bye into the second round.
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