2006 Mutua Madrileña Masters Madrid – Singles
| Singles | |
|---|---|
| 2006 Mutua Madrileña Masters Madrid | |
| Champion |
 Roger Federer
|
| Runner-up |
 Fernando González
|
| Final score | 7–5, 6–1, 6–0 |
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. All sixteen seeds received a bye into the second round.
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