The 2005–06 Liga Leumit season saw Maccabi Herzliya win the title and promotion to the Premier League. Runners-up Hakoah Amidar Ramat Gan were also promoted.
Ironi Rishon LeZion and Maccabi Be'er Sheva (playing in their first season at the second level) were relegated to Liga Artzit.
1. Two points deducted.
2. One point deducted.