The 2001 World Series, the 97th edition of Major League Baseball's championship series, took place between the Arizona Diamondbacks of the National League and the three-time defending champions New York Yankees of the American League. The Diamondbacks won the best-of-seven series four games to three. Considered one of the greatest World Series of all time, memorable aspects included two extra-inning games and three late-inning comebacks. It ended on a Game 7 walk-off hit in the form of a bases-loaded blooper single off the bat of Luis Gonzalez. This was the third World Series to end in this way, following 1997 and 1991. This was also the Yankees' fourth consecutive World Series appearance, after winning it in 1998, 1999, and 2000 (the previous year).

This was the first World Series ever played in the state of Arizona and the Mountain Time Zone. With the All-Star Game format change in 2003, the World Series would not open in the city of the National League champion again until 2010. This was the last World Series not to feature a wild card team until 2008. This was also the first World Series to end in November, due to the delay in the regular season after the September 11 attacks.

With the win by the Diamondbacks, the franchise became the first World Series champions from a Far West state other than California and the first major professional sports team from the state of Arizona to win a title.

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