2000 Epsom Derby
| Location | Epsom Downs Racecourse |
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| Date | 10 June 2000 |
| Winning horse | Sinndar |
| Starting price | 7/1 |
| Jockey | Johnny Murtagh |
| Trainer | John Oxx |
| Owner | Aga Khan IV |
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The 2000 Epsom Derby was a horse race which took place at Epsom Downs on Saturday 10 June 2000. It was the 221st running of the Derby, and it was won by Sinndar. The winner was ridden by Johnny Murtagh and trained by John Oxx. The pre-race favourite Beat Hollow finished third.
* The distances between the horses are shown in lengths or shorter. hd = head; nk = neck.
† Trainers are based in Great Britain unless indicated.
Further details of the winner, Sinndar:
Notable runs by the future Derby participants as two-year-olds in 1999.
Early-season appearances in 2000 and trial races prior to running in the Derby.
Group 1 / Grade I victories after running in the Derby.
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