2000 Acura Classic – Singles
| Singles | |
|---|---|
| 2000 Acura Classic | |
| Champion |
 Venus Williams
|
| Runner-up |
Monica Seles
|
| Final score | 6–0, 6–7(3–7), 6–3 |
Serena Williams was the defending champion, but did not compete this year.
Venus Williams won the title by defeating Monica Seles 6–0, 6–7(3–7), 6–3 in the final. It was the 3rd title for Williams in the season and the 12th title in her career.
The first four seeds received a bye into the second round.
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