The 1992 American League Championship Series was played between the Toronto Blue Jays and the Oakland Athletics from October 7 to 14, 1992. The Blue Jays won the series four games to two to advance to the World Series. The series was a rematch of the 1989 ALCS, which Oakland won in five games.

Blue Jays second baseman Roberto Alomar was named Most Valuable Player of the series. In six games, Alomar rapped 11 hits in 26 at bats for a .423 batting average, including a double and two home runs.

Oakland finished the 1992 season with a 96–66 record (.593), clinching their fourth American League West title in five years by six games over the Minnesota Twins. The Blue Jays also finished 1992 with a 96–66 mark, claiming their second straight American League East championship by four games over the Milwaukee Brewers.

The Athletics clinched the West division on September 28. Although they were not playing that day, the Twins' 9–4 loss to the Chicago White Sox at home eliminated Minnesota from contention and gave the A's the crown. The race for the East division went down to the final weekend of the season, with the Brewers leapfrogging the Baltimore Orioles for second place in mid-September. However, Toronto pulled out a 3–1 defeat of the Detroit Tigers on October 3 to secure the division title.

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