The 1992–93 Southern Football League season saw Dover Athletic win the Premier Division to earn promotion to the Football Conference.VS Rugby and Weymouth were relegated to the Midland and Southern Division respectively, whilst Dartford withdrew from the league after four matches due to financial problems and joined the Kent League the following season. Nuneaton Borough, Sittingbourne and Gresley Rovers (in their first season in the Southern League) were promoted to the Premier Division, the former two as champions. Despite finishing second in the Southern Division, Salisbury were denied promotion due to ground grading, saving Premier Division club Moor Green from relegation. Barry Town left the Southern League to join the League of Wales, whilst Andover dropped into the Wessex League.
The Premier Division featured five new clubs:
The Midland Division featured three new clubs:
The Southern Division featured four new clubs, all of which had been relegated from the Premier Division the previous season: