The 1986 National League Championship Series was a best-of-seven Major League Baseball postseason series between the NL East champion New York Mets and NL West champion Houston Astros. It is the lone MLB playoff series in which the opponents were two "expansion" teams that had begun play in the same season (1962) and was won by the Mets, four games to two, culminating with their 7–6, 16-inning triumph at Houston in Game 6. New York then defeated the Boston Red Sox in the 1986 World Series, four games to three.

After falling short of the NL East title in 1984 and 1985, the Mets, managed by Davey Johnson, captured first place in 1986 by posting a 108–54 record, 21 ¹⁄₂ games ahead of the second-place rival Philadelphia Phillies. The title was the third in Mets' history and first since winning the 1973 NL pennant.

Meanwhile, Houston recorded a mark of 96–66 to capture the NL West title, clinching the crown when staff ace Mike Scott threw a no-hitter against the San Francisco Giants, marking the first time any team had nailed down a division championship with a no-hitter. It was also the first time the Astros had won a division in six seasons. Houston was managed by Hal Lanier.

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