The 1980–81 AHL season was the 45th season of the American Hockey League. Nine teams played 80 games each in the schedule. The Hershey Bears finished first overall in the regular season. The Adirondack Red Wings won their first Calder Cup championship.
Note: GP = Games played; W = Wins; L = Losses; T = Ties; GF = Goals For; GA = Goals Against; PTS = Points;
Note: GP = Games played; G = Goals; A = Assists; Pts = Points; PIM = Penalty Minutes