During the 1972–73 English football season, Brentford competed in the Football League Third Division. The early-season departures of goalscorers John O'Mara and Bobby Ross and 15 consecutive away league defeats led to Brentford's relegation straight back to the Fourth Division.

Brentford's promotion to the Third Division at the end of the 1971–72 season meant that the club would compete in the third-tier for the first time since 1965–66. Self-imposed financial austerity since the club's relegation to the Fourth Division had enabled the club's large debts to be paid off, but despite promotion and increasing attendances, manager Frank Blunstone would again be forced to maintain a small playing squad. Blunstone turned down the chance to become assistant manager at Everton during the off-season. Released in the wake of the promotion were defender Steven Tom, midfielder Brian Turner and winger Gordon Neilson and in came amateur goalkeeper Paul Priddy, midfielders David Court and Alan Murray, winger David Jenkins and Stewart Houston's loan was turned into a permanent transfer for a £15,000 fee. The Brentford youth team was also reactivated after being disbanded due to the budget cuts of 1967, with Kevin Harding, Richard Poole and Graham Pearce being taken on as apprentices. Gary Huxley would win an England Youth cap during the season.