The 1966 Notre Dame vs. Michigan State football game is considered one of the greatest and most controversial games in college football history played between Michigan State and Notre Dame. The game was played in Michigan State's Spartan Stadium on November 19, 1966. Michigan State entered the contest 9–0 and ranked No. 2, while Notre Dame entered 8–0 and ranked #1. Notre Dame elected not to try for a score on the final series; thus, the game ended in a 10–10 tie. Notre Dame went on to win or share the national title in fourteen polls (including the AP and UPI); Michigan State won or shared in three minor polls, and Alabama, who finished with the only undefeated and untied record, won two minor polls.

Notre Dame, which had last won a National Championship in 1964 (non consensus), ranked No. 1 both the AP and Coaches' polls. Defending National Champion Michigan State, who had finished the 1965 season No. 1 in the UPI Coaches' poll, but was upset by UCLA in the Rose Bowl the previous year, entered the game ranked No. 2 in the polls. The Fighting Irish, whose bid for a National Championship two years earlier was snuffed out by USC, were hungry, while the Spartans had history and home-field advantage on their side. This was the first time in 20 years that a college football matchup was given the "Game of the Century" tag by the national media, and ABC had the nation's viewers in its grip, with equal parts Notre Dame fans and Michigan State fans. It was the tenth time in the 30-year history of the AP poll that the No. 1 team played the No. 2 team. The Spartans had defeated Notre Dame the prior year 12–3 holding Notre Dame to minus-12 yards rushing.

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