The 1963 World Series matched the two-time defending champion New York Yankees against the Los Angeles Dodgers, with the Dodgers sweeping the Series in four games to capture their second title in five years, and their third in franchise history. Starting pitchers Sandy Koufax, Don Drysdale, and Johnny Podres, and ace reliever Ron Perranoski combined to give up only four runs in four games. The dominance of the Dodgers pitchers was so complete that at no point in any of the four games did the Yankees have the lead.

This was the first time that the New York Yankees were swept in a World Series in four games (the 1922 World Series had one tie).

Of the Los Angeles Dodgers four World Series championships since the opening of Dodger Stadium, this was the only one won at Dodger Stadium. Also, of the six championships from the Dodgers franchise, it remains the only one won at home.

This series was also the first meeting between teams from New York City and Los Angeles for a major professional sports championship. Seven more such meetings have followed with three more times each in the World Series and the NBA Finals, and the 2014 Stanley Cup Finals.

Despite injuries that limited Mickey Mantle to just 65 games, the Yankees went 104–57 to win their fourth straight American League pennant—this one by 10 ¹⁄₂ games. Catcher Elston Howard (.287 BA, 28 HRs, 85 RBI) won the MVP Award, while Joe Pepitone, Roger Maris, and Tom Tresh also topped the 20 home run mark. Their pitching was anchored by Whitey Ford (24 wins, 2.74 ERA) and Jim Bouton (21 wins, 2.53 ERA).

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