1950 U.S. National Championships – Women's Singles
| Women's Singles | |
|---|---|
| 1950 U.S. National Championships | |
| Champion |
 Margaret Osborne duPont
|
| Runner-up |
Doris Hart
|
| Final score | 6–3, 6–3 |
First-seeded Margaret Osborne duPont defeated Doris Hart 6–3, 6–3 in the final to win the Women's Singles tennis title at the 1950 U.S. National Championships.
The six seeded U.S. players are listed below.Margaret Osborne duPont is the champion; others show in brackets the round in which they were eliminated.
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