1948 U.S. National Championships – Women's Singles
| Women's Singles | |
|---|---|
| 1948 U.S. National Championships | |
| Champion |
 Margaret Osborne duPont
|
| Runner-up |
Louise Brough
|
| Final score | 4–6, 6–4, 15–13 |
Third-seeded Margaret Osborne duPont defeated Louise Brough 4–6, 6–4, 15–13 in the final to win the Women's Singles tennis title at the 1948 U.S. National Championships.
The seven seeded U.S. players are listed below. Margaret Osborne duPont is the champion; others show in brackets the round in which they were eliminated.
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