1921 Uruguayan Primera División
| Season | 1921 (21st) |
|---|---|
| Champions |
 Peñarol
|
| Relegated | Reformers |
| Matches played | 132 |
| Goals scored | 300 (2.27 per match) |
The Uruguayan Championship 1921 was the 21st season of Uruguay's top-flight football league.
The tournament consisted of a two-wheel championship of all against all. It involved twelve teams, and the champion was Peñarol.
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