The 1915 College Football All-Southern Team consists of American football players selected to the College Football All-Southern Teams selected by various organizations in 1915. Josh Cody and Baby Taylor were selected third-team All-Americans by Walter Camp, and Bully Van de Graaff was selected for his second-team. Van de Graaff was Alabama's first ever All-American. Buck Mayer of the 8–1 Virginia Cavaliers was the south's first consensus All-American, selected first-team All-American by Frank G. Menke and Parke H. Davis. The "point-a-minute" Vanderbilt Commodores won the SIAA.
The composite All-Southern team selected by ten sports writers and coaches included:
Bully Van de Graaff, Baby Taylor, and Rabbit Curry were unanimous selections.
Bold = Composite selection
* = Consensus All-American
† = Unanimous selection
C = received votes for a composite All-Southern eleven selected by ten sports writers and coaches, including those from Memphis, Nashville, Atlanta, Birmingham, Chattanooga, and New Orleans. Votes for multiple positions are combined.